Microsoft Office applications support antivirus products via the Microsoft Antivirus API (Application Programming Interface). With the API, macros don't run as expected when the macro contains an encrypted Office Open XML file, such as:
With ENS, an error similar to the one below is generated when running a macro:
Security Alert: This file contains encrypted macros that have been disabled because there is no antivirus software installed that can scan them. To run these macros, remove the encryption or permission restrictions on this file. File Path: Help protect me from unknown content (recommended) Prevent encrypted macros from being scanned for viruses
NOTE: Files saved in Microsoft Office 97 or 2003 formats don't generate the error.